AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication
Kunihiko Yamashiro, Kei Hori, Suk‐King Lai, Ryo Aoki, Kazumi Shimaoka, Nariko Arimura, Saki F. Egusa, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Takaki Watanabe, Naofumi Uesaka, Masanobu Kano, Mikio Hoshino
Abstract
Loss of Auts2 leads to the reduction of cerebellar size AUTS2 promotes the dendritic maturation of Purkinje cells AUTS2 participates in PF and CF synapse development of
Topics & Concepts
NeurosciencePurkinje cellCerebellumFunction (biology)Motor functionChemistryCognitive scienceCell biologyBiologyPsychologyMedicinePhysical medicine and rehabilitationGenetics and Neurodevelopmental DisordersHearing, Cochlea, Tinnitus, GeneticsFetal and Pediatric Neurological Disorders