ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation
Qiwen Shi, Bei Hu, Chen Yang, Shufen Deng, Xiang Cheng, Jing Wu, Nan Qi
Topics & Concepts
CarcinogenesisActivating transcription factorProinflammatory cytokineCancer researchATF3Downregulation and upregulationArsenic toxicityInflammationMalignant transformationLung cancerSTAT3ArsenicChemistryBiologyImmunologyMedicineCancerSignal transductionCell biologyApoptosisInternal medicineGene expressionBiochemistryUnfolded protein responsePromoterGeneOrganic chemistryArsenic contamination and mitigationNF-κB Signaling PathwaysAcute Lymphoblastic Leukemia research