Rising Interest in the Development of Metal Complexes in Cancer Immunotherapy
Zhiyuan Li, Qing‐Hua Shen, Zong‐Wan Mao, Cai‐Ping Tan
Abstract
Metal complexes have shown great potential in cancer immunotherapy. This review briefly introduces the basic concepts and strategies of cancer immunotherapy and summarizes the recent discoveries on the immune effects of traditional platinum-based anticancer compounds. In addition, we also outline the latest research progresses on metal complexes for cancer immunotherapy focusing on platinum, ruthenium, iridium, rhenium and copper complexes. Finally, the research perspectives and unsolved problems on the applications of metallo-anticancer agents in cancer immunotherapy are purposed.
Topics & Concepts
ImmunotherapyCancer immunotherapyCancerPlatinumCancer treatmentMedicineCancer researchChemistryInternal medicineCatalysisBiochemistryNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliverySynthesis and Biological Evaluation