Facile synthesis of fully substituted 1<i>H</i>-imidazoles from oxime esters <i>via</i> dual photoredox/copper catalyzed multicomponent reactions
Shujun Cao, Chongchong Ma, Xinjie Teng, Rongshun Chen, Yun Li, Weidong Yuan, Yingguang Zhu
Abstract
A novel and efficient photoredox/copper cocatalyzed domino cyclization of oxime esters, aldehydes, and amines has been achieved, affording a broad range of fully substituted 1 H -imidazoles in good yields.
Topics & Concepts
ChemistryOximeCopperCatalysisCombinatorial chemistryDual (grammatical number)Photoredox catalysisDual roleImidazoleOrganic chemistryPhotocatalysisArtLiteratureCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques