Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold
Tarek S. Ibrahim, Ibrahim M. Salem, Samia M. Mostafa, Osama I. El‐Sabbagh, Mohamed K.M. ElKhamisi, Lamees Hegazy, Bahaa Elgendy
Topics & Concepts
CelecoxibChemistryBumetanideSelectivityPharmacologyScaffoldIn vivoEdemaAntagonistCombinatorial chemistryBiochemistryReceptorInternal medicineCatalysisMedicineMembraneIon transporterBiotechnologyBiomedical engineeringBiologySynthesis and biological activitySynthesis and Biological EvaluationSynthesis of β-Lactam Compounds