SLC17A9-PTHLH-EMT axis promotes proliferation and invasion of clear renal cell carcinoma
Weiquan Li, Ning Xu, Xiangui Meng, Hongwei Yuan, Tiexi Yu, Qi Miao, Hongmei Yang, Bo Hai, Wen Xiao, Xiaoping Zhang
Abstract
could significantly contribute to the growth of tumors. Finally, we found that SLC17A9 might be related to the drug resistance of vorinostat. Cumulatively, this study demonstrated that the SLC17A9-PTHLH-EMT axis could promote the progression of ccRCC.
Topics & Concepts
Clear cell renal cell carcinomaGene knockdownCell growthCancer researchDownregulation and upregulationEpithelial–mesenchymal transitionBiologyBiomarkerMetastasisCell cultureRenal cell carcinomaCell biologyCancerMedicinePathologyGeneBiochemistryGeneticsEpigenetics and DNA MethylationFerroptosis and cancer prognosisRenal cell carcinoma treatment