Inhibition of dynamin-related protein 1 ameliorates the mitochondrial ultrastructure via PINK1 and Parkin in the mice model of Parkinson's disease
Sitong Feng, Zhen‐Zhen Wang, Yu‐He Yuan, Xiaole Wang, Zhenyu Guo, Jinghong Hu, Yan Xu, Nai‐Hong Chen, Yi Zhang
Topics & Concepts
ParkinMitophagyPINK1DNM1LMitochondrial fissionMitochondrionDynaminCell biologyParkinson's diseaseBiologyMPTPmitochondrial fusionAutophagyMitochondrial DNAApoptosisMedicineInternal medicineDiseaseCellBiochemistryEndocytosisGeneAutophagy in Disease and TherapyMitochondrial Function and PathologyGenetics and Neurodevelopmental Disorders