AIE based GSH activatable photosensitizer for imaging-guided photodynamic therapy
You-Hui Zhang, Xue Li, Huang Li, Hyeong Seok Kim, Jusung An, Minhuan Lan, Qian‐Yong Cao, Jong Seung Kim
Abstract
A novel ferrocene decorated vinyl pyridinium-substituted tetraphenylethylene (TPEPY-S-Fc) linked by a disulfide bond was designed as a GSH activatable photosensitizer by aggregation-induced emission for imaging-guided photodynamic therapy of cancer cells.
Topics & Concepts
PhotosensitizerPhotodynamic therapyAggregation-induced emissionGlutathioneCancer therapyChemistryCancer researchFluorescencePhotochemistryCancerMedicineBiochemistryInternal medicineOpticsOrganic chemistryPhysicsEnzymeNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsSulfur Compounds in Biology