NAD+ boosting reduces age-associated amyloidosis and restores mitochondrial homeostasis in muscle
Mario Romani, Vincenzo Sorrentino, Chang‐Myung Oh, Hao Li, Tanes Lima, Hongbo Zhang, Minho Shong, Johan Auwerx
Abstract
metabolism-enhancing approaches, warranting further clinical studies.
Topics & Concepts
ProteostasisSkeletal muscleMyogenesisProteotoxicitySIRT3BiologyNAD+ kinaseMitochondrionHomeostasisMuscle atrophySirtuinSarcopeniaEndocrinologyCell biologyMyocyteInternal medicineBiochemistryMedicineProtein aggregationEnzymeMitochondrial Function and PathologyTryptophan and brain disordersAlzheimer's disease research and treatments