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The association of circulating kynurenine, a tryptophan metabolite, with frailty in older adults

Il‐Young Jang, Jin Hoon Park, Jeoung Hee Kim, Seungjoo Lee, Eun‐Ju Lee, Jin Young Lee, So Jeong Park, Da Ae Kim, Mark W. Hamrick, Beom‐Jun Kim

2020Aging43 citationsDOIOpen Access PDF

Abstract

= 0.014). These data provide clinical evidence that circulating kynurenine might be a potential biomarker for assessing the risk of frailty in humans.

Topics & Concepts

KynurenineMetaboliteAssociation (psychology)Tryptophan MetabolismTryptophanKynurenine pathwayMedicineGerontologyInternal medicinePsychologyBiologyBiochemistryAmino acidPsychotherapistTryptophan and brain disordersIntensive Care Unit Cognitive DisordersFrailty in Older Adults