Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation
Robert J. Tokarski, Chia M. Sharpe, Andrew C. Huntsman, Brittney K. Mize, Oluwatosin R. Ayinde, Emily Stahl, James R. Lerma, Andrew Reed, Bridget Carmichael, Natarajan Muthusamy, John C. Byrd, James R. Fuchs
Topics & Concepts
LinkerChemistryCyclin-dependent kinaseUbiquitin ligaseKinaseUbiquitinProtein degradationBiochemistrySmall moleculeCell cycleCellGeneOperating systemComputer scienceProtein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsUbiquitin and proteasome pathways