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Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells

Rui Han, Yao Yu, Kanghong Zhao, Jing Wei, Yuhu Hui, Jin‐Ming Gao

2022Phytomedicine37 citationsDOI

Topics & Concepts

NeuroprotectionEucommia ulmoidesProtein kinase BViability assayPI3K/AKT/mTOR pathwayPharmacologyOxidative stressApoptosisChemistryBiochemistryBiologyCell biologyMedicinePathologyAlternative medicineTraditional Chinese medicinePhytochemistry and Biological ActivitiesPlant-derived Lignans Synthesis and BioactivityParkinson's Disease Mechanisms and Treatments
Lignans from Eucommia ulmoides Oliver leaves exhibit neuroprotective effects via activation of the PI3K/Akt/GSK-3β/Nrf2 signaling pathways in H2O2-treated PC-12 cells | Litcius