Development of a facile and sensitive method for detecting alkaline phosphatase activity in serum with fluorescent gold nanoclusters based on the inner filter effect
Shengda Qi, Huanhuan Zheng, Hongyan Qin, Hong Lin Zhai
Abstract
In this work, a simple and sensitive method based on the inner filter effect (IFE) of <italic>p</italic>-nitrophenol (PNP) on the fluorescence of gold nanoclusters (AuNCs) has been developed for detecting alkaline phosphatase (ALP) activity.
Topics & Concepts
NanoclustersAlkaline phosphataseFluorescenceChemistryColloidal goldFilter paperFilter (signal processing)BiophysicsChromatographyMaterials scienceNanoparticleNanotechnologyBiochemistryEnzymeBiologyComputer scienceOpticsOrganic chemistryPhysicsComputer visionNanocluster Synthesis and ApplicationsCarbon and Quantum Dots ApplicationsAdvanced Nanomaterials in Catalysis