Glucose conjugated aza-BODIPY for enhanced photodynamic cancer therapy
Jongjit Treekoon, Thitima Pewklang, Kantapat Chansaenpak, Jaggaiah N. Gorantla, Salila Pengthaisong, Rung‐Yi Lai, James R. Ketudat Cairns, Anyanee Kamkaew
Abstract
> 100 μM) in all cell lines. Moreover, the singlet oxygen was detected inside the cancer cells after exposure to light in the presence of AZB-Glc-I. Therefore, our glucose conjugated systems proved to efficiently target cancer cells for enhanced photodynamic cancer therapy.
Topics & Concepts
BODIPYPhotodynamic therapyGlycoconjugateCancer researchWarburg effectCancerChemistryConjugated systemMedicineCancer cellBiochemistryFluorescenceInternal medicineOpticsOrganic chemistryPhysicsPolymerNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies