Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4+ T cells in chronic liver injury
Yuwei Zhang, Xue Yang, Tao Bi, Xia Wu, Lu Wang, Yafeng Ren, Yangying Ou, Chengliang Xie, Kuangjie Li, Haolong Ran, Jing Wang, Fulan Zhao, Pixian Shui, Jie Qing
Topics & Concepts
Liver injuryAntigen presentationImmunologyMHC class IIAntigenInflammationMHC class IDownregulation and upregulationEndothelial stem cellT cellBiologyMajor histocompatibility complexFibrosisMedicineCancer researchImmune systemPathologyIn vitroEndocrinologyBiochemistryGeneLiver physiology and pathologyLiver Disease Diagnosis and TreatmentLiver Disease and Transplantation