Mechanistic Insights into the Long-range Allosteric Regulation of KRAS Via Neurofibromatosis Type 1 (NF1) Scaffold Upon SPRED1 Loading
Min-Yu Li, Yuanhao Wang, Jigang Fan, Haiming Zhuang, Yaqin Liu, Dong Ji, Shaoyong Lu
Topics & Concepts
Allosteric regulationAllosteric enzymeChemistryGTPaseBiophysicsBiologyBiochemistryEnzymeCellular transport and secretionCellular Mechanics and InteractionsProtein Structure and Dynamics