A coaxial electrospun mat coupled with piezoelectric stimulation and atorvastatin for rapid vascularized bone regeneration
Jiangping Chen, Yang Su, Jinyang Wu, Chuxi Zhang, Nian Liu, Yong Zhang, Kaili Lin, Shilei Zhang
Abstract
activation of the calcium signaling pathway. This multifunctional mat coupling piezoelectric stimulation and atorvastatin promotes angiogenesis and bone regeneration, and shows great potential in the treatment of large bone defects.
Topics & Concepts
Materials sciencePiezoelectricityRegeneration (biology)CoaxialAtorvastatinBiomedical engineeringCoupling (piping)StimulationComposite materialMechanical engineeringMedicineCell biologyEngineeringInternal medicineBiologyBone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsGraphene and Nanomaterials Applications