Tandem Catalytic Systems Integrating Biocatalysts and Inorganic Catalysts Using Functionalized Porous Materials
Kara E. Metzger, Megan M. Moyer, Brian G. Trewyn
Abstract
Tandem catalysis research has recently come alive with various methods to design biosynthetic pathways utilizing enzymes and inorganic catalysts in single-pot systems. Clever applications of porous supports have brought about ways for the successful integration of incompatible enzymes and inorganic catalysts into these one-pot systems to enhance the properties of the combined catalysts. Over the past several years research in this area has shown that supports can be used to stabilize catalysts as well as act as active components within the systems. In this Perspective, we present and discuss current reports that demonstrate successful combinations of enzymes and inorganic catalysts supported on porous supports for tandem reactions and challenges yet to be overcome.