Selective stabilization of multiple promoter G-quadruplex DNA by using 2-phenyl-1H-imidazole-based tanshinone IIA derivatives and their potential suppressing function in the metastatic breast cancer
Liang Zeng, Qiong Wu, Teng Wang, Liping Li, Xuanhao Zhao, Kai Chen, Jiayi Qian, Yuan Li, Hui Xu, Wenjie Mei
Topics & Concepts
ChemistryDNAImidazoleG-quadruplexOncogeneDocking (animal)Binding selectivityCancer researchStereochemistryCombinatorial chemistryBiochemistryGeneBiologyNursingCell cycleMedicineDNA and Nucleic Acid ChemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery