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SARS-CoV-2 Brazil variants in Latin America: More serious research urgently needed on public health and vaccine protection

Chiranjib Chakraborty, Manojit Bhattacharya, Ashish Ranjan Sharma, Sang‐Soo Lee, Govindasamy Agoramoorthy

2021Annals of Medicine and Surgery21 citationsDOIOpen Access PDF

Abstract

COVID-19 has not only created a pandemic but also affected both economically and socially in all countries. It has further created a socio-economic chaos throughout Latin America. Currently, some new SARS-CoV-2 variants are circulating in Latin America and one among the significant variant belongs to the P.1 lineage (B.1.1.28.1) that has 17 mutations. The essential modifications located in the spike glycoprotein RBD include E484K, K417T and N501Y. Along with the P.1 lineage, P.2 lineage (B.1.1.28.2) has also appeared recently. Details on all the variants are unknown, along with the Brazil variants at this time. Therefore, we call for intensive research to collect more data to understand the variants’ virulence and the effects on vaccine efficacy. HIGHLIGHTS The COVID-19 pandemic has affected socially and economically the entire world, including Latin America. Recently, a significant variant of COVID-19 was found in Brazil, known as lineage P.1. Two other variants (P.2 Lineage and B.1.1.7 lineage) are currently circulating across Latin America. We urge the scientific community to research the new emerging variants of SARS-CoV-2 intensively.

Topics & Concepts

Lineage (genetic)Latin AmericansPandemicPublic healthSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyCoronavirus disease 2019 (COVID-19)MedicineBiologyGeneticsGenePolitical scienceDiseaseInfectious disease (medical specialty)NursingPathologyLawSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studiesvaccines and immunoinformatics approaches
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