The effect of drug loading on the properties of abiraterone–hydroxypropyl beta cyclodextrin solid dispersions processed by solvent free KinetiSol® technology
Urvi Gala, Dave A. Miller, Yongchao Su, Angela Spangenberg, Robert O. Williams
Topics & Concepts
Abiraterone acetateBioavailabilityChemistryIn vivoPharmacokineticsDifferential scanning calorimetryDrugPharmacologyDissolutionProdrugCyclodextrinAbirateroneChromatographyMaterials scienceProstate cancerOrganic chemistryBiochemistryMedicineCancerThermodynamicsInternal medicineBiotechnologyBiologyAndrogen receptorPhysicsAndrogen deprivation therapyDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesProtein purification and stability