COVID-19 and hyperglycemia/diabetes
Konstantinos Michalakis, Ιoannis Ilias
Abstract
In early studies regarding coronavirus disease 2019 (COVID-19), type 2 diabetes mellitus was considered to contribute substantially to the disease's inflammatory response. Subsequently, even hyperglycemia, regardless of insulin resistance or diabetes mellitus, was found to be additionally harmful. Recent studies have shown inflammation of the pancreatic β cells in COVID-19, even leading to new onset diabetes mellitus. We hereby summarize core literature on glycemia and COVID-19, and present implicated pathways and mechanisms.
Topics & Concepts
MedicineCoronavirus disease 2019 (COVID-19)Diabetes mellitus2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus InfectionsVirologyInternal medicineDiseaseEndocrinologyOutbreakInfectious disease (medical specialty)COVID-19 Clinical Research StudiesDiabetes and associated disordersDiabetes Management and Research