Novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as MAO-B inhibitors: Synthesis, biological evaluation and molecular modeling studies
Fatih Tok, Zefine Uğraş, Begüm Nurpelin Sağlık, Yusuf Özkay, Zafer Asım Kaplancıklı, Bedia Koçyiğit‐Kaymakçıoğlu
Topics & Concepts
ChemistryOxadiazoleMonoamine oxidaseMoietySubstituentStereochemistryMonoamine oxidase BCarbon-13 NMRMonoamine oxidase AProton NMRDocking (animal)EnzymeBiochemistryOrganic chemistryNursingMedicineCholinesterase and Neurodegenerative DiseasesElectrochemical sensors and biosensorsSynthesis and biological activity