Synthesis, docking and evaluation of in vitro anti-inflammatory activity of novel morpholine capped β-lactam derivatives
Roghayeh Heiran, Saghi Sepehri, Aliasghar Jarrahpour, Carole Digiorgio, Hana Douafer, Jean Michel Brunel, Ahmad Gholami, Elham Riazimontazer, Edward Turos
Topics & Concepts
ChemistryMorpholineDocking (animal)ADMEStereochemistrySubstituentNitric oxide synthaseCytotoxicityNitric oxideIn vitroKeteneBenzothiazoleCycloadditionAnti-inflammatoryEnzymeBiochemistryOrganic chemistryPharmacologyNursingMedicineCatalysisSynthesis of β-Lactam CompoundsSynthesis and Biological EvaluationSynthesis and Catalytic Reactions