Fingolimod exerts neuroprotection by regulating S1PR1 mediated BNIP3-PINK1-Parkin dependent mitophagy in rotenone induced mouse model of Parkinson's disease
Shruti Rajan, Anika Sood, Rachit Jain, Pushpa Tryphena Kamatham, Dharmendra Kumar Khatri
Topics & Concepts
PINK1MitophagyNeuroprotectionParkinRotenoneSubstantia nigraParkinson's diseaseFingolimodPharmacologyMPTPNeurodegenerationBiologyDopaminergicMitochondrionMedicineAutophagyCell biologyNeuroscienceDopamineImmunologyInternal medicineBiochemistryApoptosisDiseaseMultiple sclerosisAutophagy in Disease and TherapySphingolipid Metabolism and SignalingLysosomal Storage Disorders Research