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Evaluation of Early Warning, Alert and Response System for Ebola Virus Disease, Democratic Republic of the Congo, 2018–2020

Mory Keïta, Héloïse Lucaccioni, Michel Kalongo Ilumbulumbu, Jonathan A. Polonsky, Justus Nsio-Mbeta, Gaston Tshapenda Panda, Pierre Celeste Adikey, John Kombe Ngwama, Michel Kasereka Tosalisana, Boubacar Diallo, Lorenzo Subissi, Adama Dakissaga, Iris Finci, Maria Moitinho de Almeida, Debarati Guha‐Sapir, Ambrose Talisuna, Alexandre Délamou, Stéphanie Dagron, Olivia Keiser, Steve Ahuka‐Mundeke

2021Emerging infectious diseases25 citationsDOIOpen Access PDF

Abstract

The 10th and largest Ebola virus disease epidemic in the Democratic Republic of the Congo (DRC) was declared in North Kivu Province in August 2018 and ended in June 2020. We describe and evaluate an Early Warning, Alert and Response System (EWARS) implemented in the Beni health zone of DRC during August 5, 2018-June 30, 2020. During this period, 194,768 alerts were received, of which 30,728 (15.8%) were validated as suspected cases. From these, 801 confirmed and 3 probable cases were detected. EWARS showed an overall good performance: sensitivity and specificity >80%, nearly all (97%) of alerts investigated within 2 hours of notification, and good demographic representativeness. The average cost of the system was US $438/case detected and US $1.8/alert received. The system was stable, despite occasional disruptions caused by political insecurity. Our results demonstrate that EWARS was a cost-effective component of the Ebola surveillance strategy in this setting.

Topics & Concepts

Ebola virusRepresentativeness heuristicMedicineEnvironmental healthWarning systemDisease surveillanceDemocracyDiseaseOutbreakVirologyDemographyPolitical sciencePoliticsInternal medicineComputer scienceStatisticsLawTelecommunicationsMathematicsSociologyViral Infections and Outbreaks ResearchCOVID-19 epidemiological studiesCOVID-19 Digital Contact Tracing