The introduction of immunosuppressor (TDO inhibitor) significantly improved the efficacy of irinotecan in treating hepatocellular carcinoma
Qingqing Liu, Shixian Hua, Xinyi Wang, Feihong Chen, Shao-Hua Gou
Topics & Concepts
IrinotecanCancer researchApoptosisTumor microenvironmentImmune systemChemistryCancer cellIn vivoCamptothecinImmune checkpointCancerPharmacologyImmunotherapyColorectal cancerBiologyMedicineBiochemistryImmunologyInternal medicineBiotechnologyTryptophan and brain disordersImmune cells in cancerCancer, Stress, Anesthesia, and Immune Response