Whole-Cell Production of Patchouli Oil Sesquiterpenes in <i>Escherichia coli</i>: Metabolic Engineering and Fermentation Optimization in Solid–Liquid Phase Partitioning Cultivation
Francisco Aguilar, Kimia Ekramzadeh, Thomas Scheper, Sascha Beutel
Abstract
by solid-liquid phase partitioning cultivation, which provides new insights for the development of sustainable bioprocesses for the microbial production of fragrant terpenes.
Topics & Concepts
PatchouliFermentationBioreactorDownstream processingChemistryFood scienceEscherichia coliPogostemonMetabolic engineeringBioprocess engineeringBiochemistryChromatographyBiologyEssential oilBiotechnologyOrganic chemistryEnzymeTraditional medicineMedicineGenePlant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisBiochemical and biochemical processes