Activated single nucleotide mismatch determination through toehold-embedded hairpin-mediated strand displacement reaction alongside CRISPR-Cas12a for detection of TP53 point mutation
David Septian Sumanto Marpaung, Shih Sheng Jiang, Wen‐Tsen Fang, Yu-Chieh Liao, Min‐Chieh Chuang
Topics & Concepts
CRISPRPoint mutationDisplacement (psychology)MutationNucleotideChemistryGeneticsBiologyMolecular biologyGenePsychotherapistPsychologyCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms