Litcius/Paper detail

Identification of novel piperazine-tethered phthalazines as selective CDK1 inhibitors endowed with in vitro anticancer activity toward the pancreatic cancer

Laila Akl, Amer Ali Abd El‐Hafeez, Tamer M. Ibrahim, Rofaida Salem, Hala Mohamed M. Marzouk, Ramadan A. El-Domany, Pradipta Ghosh, Wagdy M. Eldehna, Sahar M. Abou‐Seri

2022European Journal of Medicinal Chemistry33 citationsDOIOpen Access PDF

Topics & Concepts

Cyclin-dependent kinase 1ChemistryKinaseCell cycleCancer researchCell cultureIC50Pancreatic cancerIn vitroPharmacologyCellBiochemistryCancerInternal medicineBiologyMedicineGeneticsCancer-related Molecular PathwaysNeuroblastoma Research and TreatmentsCancer therapeutics and mechanisms