The Association between Circulating microRNAs and the Risk of Active Disease Development from Latent Tuberculosis Infection: a Nested Case-Control Study
Henan Xin, Xuefang Cao, Ying Du, Jiaoxia Yan, Rui He, Zisen Liu, Haoran Zhang, Yijun He, Bin Zhang, Dakuan Wang, Ling Guan, Fei Shen, Boxuan Feng, Zhusheng Quan, Yongpeng He, Jianmin Liu, Qi Jin, Shouguo Pan, Lei Gao
Abstract
Approximately a quarter of the world population are infected with M. tuberculosis and about 5% to 10% of these might develop active disease in their lifetime. Preventive treatment could effectively protect individuals at a high risk of developing active disease from LTBI, and is regarded as a critical component of End TB Strategies.
Topics & Concepts
TuberculosisNested case-control studyAssociation (psychology)DiseaseLatent tuberculosisCase-control studyActive tuberculosisMedicinemicroRNAImmunologyBiologyMycobacterium tuberculosisGeneticsInternal medicinePathologyPsychologyGenePsychotherapistMicroRNA in disease regulationExtracellular vesicles in diseaseCircular RNAs in diseases