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Self-Catalyzed, Visible-Light-Induced Selective C3–H Aroylation of Quinoxalin-2(1<i>H</i>)-ones with Arylaldehydes by Air as an Oxidant

Wenhao Liu, Xingyuan Liu, Runjiao Liu, Hanqing Zhao, Zihao Xia

2024The Journal of Organic Chemistry18 citationsDOI

Abstract

A self-catalyzed, visible-light-induced, directly selective C3–H aroylation of quinoxalin-2(1 H )-ones via energy transfer and hydrogen atom transfer (HAT) catalysis has been developed. The method is highly atom-economical, eco-friendly, and easy to handle. Notably, the reaction proceeded efficiently with ambient air as the sole oxidant at room temperature.

Topics & Concepts

ChemistryCatalysisVisible spectrumPhotochemistryMedicinal chemistryCombinatorial chemistryOrganic chemistryOptoelectronicsPhysicsRadical Photochemical ReactionsCO2 Reduction Techniques and CatalystsCatalytic C–H Functionalization Methods
Self-Catalyzed, Visible-Light-Induced Selective C3–H Aroylation of Quinoxalin-2(1<i>H</i>)-ones with Arylaldehydes by Air as an Oxidant | Litcius