The antipsychotropic drug Duloxetine rescues PAX6 haploinsufficiency of mutant limbal stem cells through inhibition of the MEK/ERK signaling pathway
Orly Dorot, Lauriane N. Roux, Léa Zennaro, Keren Oved, Dominique Brémond‐Gignac, Edward Pichinuk, Daniel Aberdam
Topics & Concepts
PAX6AniridiaDuloxetineMedicineHaploinsufficiencyMAPK/ERK pathwayPharmacologyBiologyPhenotypeCell biologySignal transductionPathologyGeneticsTranscription factorGeneAlternative medicineCorneal Surgery and TreatmentsConnexins and lens biologyDevelopmental Biology and Gene Regulation