A Novel UHPLC–MS/MS Method Development and Validation for Identification and Quantification of Genotoxic Impurity Bis (2-Chloroethyl) Amine in Aripiprazole Drug Substance
Krishna Moorthy Manchuri, Mahammad Ali Shaik, G. V. REDDY
Topics & Concepts
ChemistryChromatographyDetection limitAmine gas treatingFormic acidElectrospray ionizationMass spectrometrySelected reaction monitoringElutionAnalytical Chemistry (journal)Tandem mass spectrometryOrganic chemistryAnalytical Chemistry and ChromatographyAnalytical Methods in PharmaceuticalsSynthesis and Biological Evaluation