Dual-responsive nano-prodrug micelles for MRI-guided tumor PDT and immune synergistic therapy
Hui Guo, Fangzhe Liu, Enqi Liu, Shanshan Wei, Wenbo Sun, Baoqiang Liu, Guoying Sun, Lehui Lu
Abstract
results illustrated that the micelles had good biocompatibility and biosafety. On the basis of the efficient drug delivery strategies in PDT and IDO pathway inhibition, this intelligent dual-drug delivery system could serve as an effective approach for MRI guided combination therapy of cancer.
Topics & Concepts
MicelleNanocarriersProdrugPhotodynamic therapyDrug deliveryTumor microenvironmentPhotosensitizerIn vivoBiocompatibilityDrugCancer researchChemistryMaterials scienceBiophysicsPharmacologyNanotechnologyMedicineOrganic chemistryAqueous solutionTumor cellsBiotechnologyBiologyNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismImmune cells in cancer