Verubulin and its derivatives: Progress and promise in tubulin-targeted cancer therapy
Alireza Mousavi, Mahfam Moradi, Loghman Firoozpour, Alireza Foroumadi
Topics & Concepts
Cancer therapyChemistryMicrotubuleTubulinComputational biologyTherapeutic windowCancer treatmentPharmacologyCancer researchGlioblastomaCancerEpothiloneClinical trialMolecular imagingMetabolic stabilityTargeted therapyPhenotypic screeningNeuroscienceColchicineBioinformaticsDrug discoveryCombination therapyMechanism (biology)MitosisPotencyAntimitotic AgentCancer therapeutics and mechanismsToxin Mechanisms and ImmunotoxinsSynthesis and biological activity