A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
Suling Huang, Yanwei Wu, Zhuohui Zhao, Bing Wu, Kai Sun, Haoyu Wang, Qin Li, Fang Bai, Ying Leng, Wei Tang
Topics & Concepts
InflammasomeObeticholic acidMechanism (biology)ChemistryMacrophageCell biologyPharmacologyMedicineBiochemistryBiologyPhysicsAgonistReceptorQuantum mechanicsIn vitroLiver Disease Diagnosis and TreatmentInflammasome and immune disordersLiver Diseases and Immunity