Lipidomics and Comparative Metabolite Excretion Analysis of Methanogenic Archaea Reveal Organism-Specific Adaptations to Varying Temperatures and Substrate Concentrations
Ruth-Sophie Taubner, Lydia Baumann, Michael Steiner, Kevin Pfeifer, Barbara Reischl, Kordian Korynt, Thorsten Bauersachs, Barbara Mähnert, Elisabeth L. Clifford, Jörn Peckmann, Bernhard Schuster, Daniel Birgel, Simon K.‐M. R. Rittmann
Abstract
Biological methane production by methanogenic archaea has been well studied for biotechnological purposes. This study reveals that methanogenic archaea actively modulate their lipid inventory and proteinogenic amino acid excretion pattern in response to environmental changes and the possible utilization of methanogenic archaea as microbial cell factories for the targeted production of lipids and amino acids.
Topics & Concepts
ArchaeaBiochemistryMetaboliteLipidomicsBiologyAmino acidOrganismSubstrate (aquarium)BacteriaChemistryEcologyGenePaleontologyGeneticsMethane Hydrates and Related PhenomenaMicrobial Community Ecology and PhysiologyMicrobial Metabolic Engineering and Bioproduction