Litcius/Paper detail

The Potential for Kratom as an Antidepressant and Antipsychotic.

Lindsay E Johnson, Lilian Balyan, Amy Magdalany, Fizza Saeed, Robert Salinas, Starla Wallace, Charles A. Veltri, Marc T. Swogger, Zach Walsh, Oliver Grundmann

2020PubMed44 citationsOpen Access PDF

Abstract

), and alpha-2 adrenergic receptors displaying possible indications of kratom to be used as both antipsychotics and antidepressants. Although studies to evaluate this effect are still lacking, several online and in-person surveys note relief of depression and anxiety symptoms among those who consume kratom products, and in fact identify it as a common reason for consumption. This then highlights the dire need for further research to be conducted on kratom, its mechanism of action and the constituents that elicit these antidepressant, anxiolytic, and antipsychotic properties.

Topics & Concepts

AntipsychoticAntidepressantAnxiolyticPharmacologyOpioidMedicineAnxietyPsychiatryTraditional medicineReceptorSchizophrenia (object-oriented programming)Internal medicineAlkaloids: synthesis and pharmacologyTraditional and Medicinal Uses of AnnonaceaeTryptophan and brain disorders