Litcius/Paper detail

Electrochemical <i>N</i>-acylation and <i>N</i>-α-ketoacylation of sulfoximines <i>via</i> the selective decarboxylation and dehydration of α-ketoacids

Chen Kang, Mingzhe Li, Wenxiu Huang, Shoucai Wang, Mengyu Peng, Longqiang Zhao, Guangbin Jiang, Fanghua Ji

2023Green Chemistry35 citationsDOI

Abstract

We describe an electrochemical N -acylation and N -α-ketoacylation of sulfoximines via the selective decarboxylation and dehydration of α-ketoacids using electricity as a “traceless” oxidant and α-ketoacid as a selective “acyl” or “α-ketoacyl” source.

Topics & Concepts

DecarboxylationAcylationDehydrationChemistryElectrochemistryOrganic chemistryBiochemistryCatalysisElectrodePhysical chemistrySynthesis and Catalytic ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques