Litcius/Paper detail

BRD4 inhibitor MZ1 exerts anti-cancer effects by targeting MYCN and MAPK signaling in neuroblastoma

Xianbing Zhang, Xinyi Guo, Ran Zhuo, Yanfang Tao, Wenxia Liang, Randong Yang, Yanling Chen, Haibo Cao, Si-qi Jia, Juanjuan Yu, Xinmei Liao, Xiaolu Li, Fang Fang, Gen Li, Di Wu, Yunyun Xu, Zhiheng Li, Jian Pan, Jian Wang

2022Biochemical and Biophysical Research Communications30 citationsDOI

Topics & Concepts

NeuroblastomaCancer researchBromodomainBRD4ApoptosisMAPK/ERK pathwayBET inhibitorCell cycleBiologyTargeted therapySignal transductionChemistryCancerGeneCell cultureEpigeneticsCell biologyGeneticsProtein Degradation and InhibitorsNeuroblastoma Research and TreatmentsUbiquitin and proteasome pathways