Cec4-Derived Peptide Inhibits Planktonic and Biofilm-Associated Methicillin Resistant Staphylococcus epidermidis
Chengju Mao, Yue Wang, Yifan Yang, Lu Li, Kexin Yuan, Huijun Cao, Zhilang Qiu, Guo Guo, Jian-Wei Wu, Jian Peng
Abstract
S. epidermidis is one of the most important pathogens of graft-related infection and hospital-acquired infection. The growing problem of antibiotic resistance, as well as the emergence of bacterial pathogenicity, highlights the need for antimicrobials with new modes of action.
Topics & Concepts
Staphylococcus epidermidisMicrobiologyVirulenceBiofilmPeptideBiologyAntimicrobialReactive oxygen speciesBacteriaStaphylococcus aureusChemistryBiochemistryGeneGeneticsAntimicrobial Peptides and ActivitiesBiochemical and Structural CharacterizationBacterial biofilms and quorum sensing