Oxygen sensitivity of [FeFe]-hydrogenase: a comparative study of active site mimics inside <i>vs.</i> outside the enzyme
Shanika Yadav, Rieke Haas, Esma Birsen Boydas, Michael Roemelt, Thomas Happe, Ulf‐Peter Apfel, Sven T. Stripp
Abstract
is developed. Our study underscores the relevance of model systems in understanding biocatalysis and validates their potential as important tools for elucidating the chemistry of oxygen-induced deactivation of [FeFe]-hydrogenase.
Topics & Concepts
HydrogenaseActive siteOxygenActive oxygenSensitivity (control systems)ChemistryEnzymeCofactorPhotochemistryBiochemistryOrganic chemistryElectronic engineeringEngineeringMetalloenzymes and iron-sulfur proteinsElectrocatalysts for Energy ConversionCatalysis and Hydrodesulfurization Studies