A 5-fluorouracil–kaempferol drug–drug cocrystal: a ternary phase diagram, characterization and property evaluation
Wenting Lv, Xiaoxu Liu, Xia-Lin Dai, Xiang-Tian Long, Jia‐Mei Chen
Abstract
A drug–drug cocrystal of 5-fluorouracil and kaempferol was comprehensively investigated and exhibits optimized solubility behavior in comparison with individual APIs.
Topics & Concepts
CocrystalKaempferolDrugSolubilityTernary operationChemistryMaterials sciencePharmacologyCombinatorial chemistryOrganic chemistryMedicineComputer scienceFlavonoidMoleculeHydrogen bondProgramming languageAntioxidantCrystallography and molecular interactionsCrystallization and Solubility StudiesEnzyme Structure and Function