Aspartame and sucralose extend the lifespan and improve the health status of<i>C. elegans</i>
Mohan Zhang, Shuai Chen, Yu-Hua Dai, Ting Duan, Yu Xu, Xiaolin Li, Jun Yang, Xinqiang Zhu
Abstract
Aspartame and sucralose increased the lifespan, reduced lipofuscin accumulation, and transiently increased motility in C. elegans , and we hypothesized that the hormesis effect might be the underlying mechanism.
Topics & Concepts
AspartameSucraloseCaenorhabditis elegansBiologyFood scienceBiochemistryGeneGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninDiet and metabolism studies