Modelling Graft-Versus-Host Disease in Mice Using Human Peripheral Blood Mononuclear Cells
Manjurul Haque, Dominic Boardman, Avery J. Lam, Katerine MacDonald, Lieke Sanderink, Qing Huang, Vivian Fung, Sabine Ivison, Majid Mojibian, Megan K. Levings
Abstract
Sci Transl Med (2020), DOI: 10.1126/scitranslmed.aaz3866 Graphical abstract.
Topics & Concepts
Humanized mouseGraft-versus-host diseaseHematopoietic stem cell transplantationPeripheral blood mononuclear cellImmunologyImmune systemStem cellTransplantationHaematopoiesisMedicineIn vivoDiseaseEx vivoT cellNodBiologyIn vitroPathologyInternal medicineCell biologyBiotechnologyBiochemistryHematopoietic Stem Cell TransplantationImmune Cell Function and InteractionT-cell and B-cell Immunology