Fluorescence biosensor for DNA methyltransferase activity and related inhibitor detection based on methylation-sensitive cleavage primer triggered hyperbranched rolling circle amplification
Liping Chen, Ying Zhang, Qian Xia, Fang Luo, Longhua Guo, Bin Qiu, Zhenyu Lin
Topics & Concepts
ChemistryDNAMethylationDetection limitFluorescenceRolling circle replicationPrimer (cosmetics)Cleavage (geology)BiosensorMethyltransferaseDNA methylationSYBR Green IMolecular biologyBiophysicsLysisBiochemistryGeneGene expressionReal-time polymerase chain reactionChromatographyBiologyDNA replicationPhysicsPaleontologyOrganic chemistryFracture (geology)Quantum mechanicsAdvanced biosensing and bioanalysis techniquesEpigenetics and DNA MethylationDNA and Nucleic Acid Chemistry