Tandem Photoredox and Copper-Catalyzed Decarboxylative C(sp<sup>3</sup>)–N Coupling of Anilines and Imines Using an Organic Photocatalyst
Guido Barzanò, Runze Mao, Marion Garreau, Jérôme Waser, Xile Hu
Abstract
An organic photoredox catalyst, 4CzIPN, was used in combination with a copper catalyst, CuCl, to effect decarboxylative C(sp3)–N coupling. The coupling worked with both anilines and imines as nitrogen sources and could be used to prepare a variety of alkyl amines from readily available alkyl carboxylic acids.
Topics & Concepts
ChemistryCatalysisAlkylTandemCopperPhotocatalysisPhotoredox catalysisCoupling (piping)NitrogenOrganic chemistryCombinatorial chemistryComposite materialEngineeringMechanical engineeringMaterials scienceRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques