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Exploring Carbohydrates for Therapeutics: A Review on Future Directions

Jie Wang, Yukun Zhang, Qi Lu, Dongming Xing, Renshuai Zhang

2021Frontiers in Pharmacology54 citationsDOIOpen Access PDF

Abstract

Carbohydrates are important components of foods and essential biomolecules performing various biological functions in living systems. A variety of biological activities besides providing fuel have been explored and reported for carbohydrates. Some carbohydrates have been approved for the treatment of various diseases; however, carbohydrate-containing drugs represent only a small portion of all of the drugs on the market. This review summarizes several potential development directions of carbohydrate-containing therapeutics, with the hope of promoting the application of carbohydrates in drug development.

Topics & Concepts

CarbohydrateChemistryBiomoleculeBiotechnologyComputational biologyBiochemical engineeringBiochemistryBiologyEngineeringCarbohydrate Chemistry and SynthesisGlycosylation and Glycoproteins ResearchEnzyme Catalysis and Immobilization