Single-cell RNA-sequencing analyses identify heterogeneity of CD8+ T cell subpopulations and novel therapy targets in melanoma
Weiwei Deng, Yubo Ma, Zhen Su, Yufang Liu, Panpan Liang, Chen Huang, Xiao Liu, Jin Shao, Yi Zhang, Kai Zhang, Jian Chen, Ruoyu Li
Abstract
could serve as potential targets for melanoma therapy.
Topics & Concepts
Cytotoxic T cellCD8BiologyMelanomaT cellImmunotherapyCellCancer researchTumor microenvironmentImmunologyImmune systemGeneticsIn vitroSingle-cell and spatial transcriptomicsT-cell and B-cell ImmunologyCAR-T cell therapy research